This is a peculiar philosophy that I have a hard time relating to --- why is replacing a connector "alteration" while replacing a board in the overall cube is not?
Usage and time cause wear.
I also have what may be some alarming news about the historic 47 uF surface-mount and 220 uF through-hole capacitors on your processor board and (if you have one) sound box circuit board --- as well as (and especially) the 10000 uF ELNA "Long Life" (lol) capacitors on the analog board in your N4000-series monitor (if you have one). You may find that they are leaching a considerable amount of hard-to-repair history all over your hardware as we speak.
PS: Per this pinout page, pin 22B is one of many ground pins, and your computer should work just fine without it. If I were in your shoes I would do nothing about the missing pin.